Tackling Two Titans: How to Combat Rheumatoid Arthritis and Heart Failure Simultaneously

March 16, 2023
By Elaine Loja
6 min read

Rheumatoid arthritis (RA) affects the joints, leading to inflammation, pain, and stiffness. However, RA can also cause systemic inflammation, affecting other organs, including the heart, leading to heart failure (HF).

Tackling Two Titans: How to Combat Rheumatoid Arthritis and Heart Failure Simultaneously

Tackling Two Titans: How to Combat Rheumatoid Arthritis and Heart Failure Simultaneously

Knowledge is power, and we can reduce the risk of heart failure by proactively managing RA and heart health. This includes regular check-ups, medication, and lifestyle modifications like exercise, a heart-healthy diet, and quitting smoking.

Early detection and treatment of heart failure can also prevent complications and improve outcomes. By doing so, we can protect ourselves and our loved ones from the dangers of heart failure and live our lives to the fullest.

What Is the Link Between Rheumatoid Arthritis and Heart Failure?

RA and heart failure may seem like two completely different conditions, but they are connected in more ways than one. For example, chronic inflammation, a key feature of RA, can cause damage to blood vessels over time, leading to heart disease.

Moreover, medications used to treat RA can have side effects on the heart. These connections highlight the need for holistic management of RA patients, including closely monitoring cardiovascular health.

Causes of Rheumatoid Arthritis and Heart Failure

Genetic Factors

Our genes are like the blueprint that determines our body's functioning, and in the case of rheumatoid arthritis and heart failure, they can cause the problem.

For example, with rheumatoid arthritis, specific genetic markers can influence the immune system, leading to inflammation and joint damage. In heart failure, genetic mutations can affect the structure or function of the heart, causing it to weaken over time.

However, genes are not the only cause; their influence can vary among individuals. Thus, while genetics may set the stage, other factors must come into play to develop these conditions.

Environmental Factors

Our bodies exist in an environment that can influence our health and well-being, and rheumatoid arthritis and heart failure are no exception.

For example, in rheumatoid arthritis, environmental triggers such as smoking, pollution, and infections can activate the immune system and cause joint inflammation. Similarly, in heart failure, exposure to environmental toxins such as air pollution can contribute to heart damage.

Moreover, lifestyle factors such as a lack of exercise, poor diet, and stress can increase inflammation and contribute to both conditions. While it is not always possible to control the environment, being aware of its effects can help us to manage and prevent these conditions.

Heart Failure and Rheumatoid Arthritis Symptoms:

RA Symptoms

The symptoms of RA typically include joint pain and stiffness, particularly in the small joints of the hands and feet. In addition, the joints may feel warm or tender to the touch, and movement may be limited or difficult.

Other common symptoms of RA may include fatigue, fever, weight loss, and overall weakness. RA can also affect other body parts, such as the eyes, lungs, and heart. Early detection and treatment can help manage symptoms and prevent further joint damage.

HF Symptoms

Common symptoms may include shortness of breath, fatigue, swelling in the legs, ankles, or feet, and rapid or irregular heartbeat. People with HF may also experience coughing, wheezing, or difficulty breathing, especially when lying down.

As HF progresses, symptoms may become more severe, including chest pain, loss of appetite, and confusion. Early diagnosis and treatment can help manage symptoms and improve quality of life.

Diagnosis of Rheumatoid Arthritis and Heart Failure:

Tests for RA

Rheumatoid Arthritis (RA) is a tricky condition to diagnose since its symptoms can mimic those of other forms of arthritis, making it essential to utilize a combination of clinical evaluation and laboratory tests.

Therefore, RA diagnosis often begins with a physical examination, where a rheumatologist evaluates the patient's joint movement, tenderness, and overall condition.

Further laboratory testing includes the identification of RA-specific antibodies such as Rheumatoid Factor and Anti-CCP, CRP, and ESR to monitor inflammation levels.

In addition, imaging techniques like X-rays, MRI, or ultrasound can reveal joint damage, inflammation, and bone erosion. These diagnostic tests provide a comprehensive picture of the disease, enabling medical professionals to identify RA early and begin prompt treatment.

Tests for HF

Heart Failure (HF) diagnosis involves a multi-faceted approach, including physical examination, imaging studies, and laboratory tests. The clinical evaluation assesses the patient's symptoms, including shortness of breath, fatigue, and edema.

The physical examination is crucial in detecting the presence of heart abnormalities, including abnormal heart sounds, increased jugular venous pressure, and fluid accumulation in the lungs or lower extremities.

Imaging studies like echocardiography or cardiac MRI can identify changes in heart size, function, and valve abnormalities. In addition, laboratory tests such as blood tests for BNP and NT-proBNP can indicate heart failure, and other tests like ECG or stress tests can evaluate heart function and exercise capacity.

With such a comprehensive diagnosis, healthcare professionals can provide prompt treatment and help prevent the progression of HF.

Are There Any Treatments Available to Manage Rheumatoid Arthritis-Related Heart Failure?

Medication for RA

Disease-modifying antirheumatic drugs (DMARDs) are a cornerstone of treatment for RA. These medications, such as methotrexate and sulfasalazine, can help to reduce inflammation and prevent joint damage.

But they can also positively impact the heart, as inflammation is a key factor in developing heart failure. In addition, biologic agents, such as TNF and interleukin-6 inhibitors, can also effectively manage RA and reduce inflammation.

Medication for HF

When it comes to heart failure, medication options are plentiful. Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) can help to reduce blood pressure and relax blood vessels, easing the workload on the heart.

Beta-blockers can slow the heart rate and reduce the heart's workload. Diuretics can help to reduce fluid buildup in the body, relieving symptoms such as shortness of breath and swelling. Other medications, such as aldosterone antagonists and digoxin, can also improve heart function.

Risk Factors of Rheumatoid Arthritis and Heart Failure:

Risk Factors for RA

Several factors can increase the risk of developing RA, including genetics, age, gender, environmental factors such as smoking, obesity, and exposure to certain toxins. In addition, a family history of RA, autoimmune diseases, and infections can also increase the risk of developing RA.

Risk Factors for Heart Failure

Some risk factors for heart failure include high blood pressure, coronary artery disease, diabetes, obesity, smoking, and a family history of heart disease. Additionally, certain medications, such as chemotherapy and nonsteroidal anti-inflammatory drugs (NSAIDs), can increase the risk of heart failure.

Are There Any Prevention Methods to Reduce the Risk of Rheumatoid Arthritis-Related Heart Failure:

Prevention of Rheumatoid Arthritis

While there is no guaranteed way to prevent RA, some measures can be taken to reduce the risk. These include maintaining a healthy weight, avoiding smoking, and limiting exposure to environmental toxins. Additionally, staying physically active and eating a balanced diet with plenty of fruits and vegetables can help support overall health and reduce the risk of chronic diseases.

Prevention of Heart Failure

You can take several steps to reduce the risk of heart failure, including managing high blood pressure, controlling diabetes, maintaining a healthy weight, avoiding smoking, limiting alcohol intake, and staying physically active.

Additionally, following a heart-healthy diet that is low in saturated and trans fats and high in fruits, vegetables, and whole grains can also help to reduce the risk of heart failure. Regular check-ups with a healthcare provider can also help to identify and manage any risk factors early on.

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